Life Science

Microwell Arrays: High Sample Density
and Greater Efficiency

Researchers use microwell arrays to gather more data reliably from fluorescence- and luminescence-based assays. The microwell arrays support sensitive biological and bioterrorism analyses and offer economic advantages over conventional arrays. Part of the advantage of these arrays is that their high sample density allows for thousands of simultaneous reactions to take place, saving money and time when studying complex test variables.

INCOM’s etched microwell arrays provide over 1 million individual wells on a standard microscope slide. Acting as tiny test tubes, each of the 1 million wells can support a reaction and each well can be “read” using sensors. In fact, INCOM’s fiber optic microwells arrays are over 200 times more efficient than even the most advanced 1536-well microplates in delivering information to automated bottom readers.

Precise Results for Direct Contact Imaging

When used with microarray printing technology, fiber optic plates can increase the quantity of individual experiments in a designated location. High signal-to-noise ratio and direct contact imaging allow fiber optic bottom plates to present millions of noise-free, distortion-free images on exactly the same plane to inverted microscopes, bottom readers, and CCDs. This form of direct contact imaging eliminates focusing and increases sensitivity, spatial resolution, and well-to-well consistency to ensure precise, valid results.

Fiber Optics Provide More Perfect Images
than Any Other Technology

INCOM’s fiber optic bottom plates transfer the image from the well bottom to the surface using millions of optically-isolated individual fibers to transfer the image. The result? Crosstalk is eliminated and resolution increases significantly. In contrast, glass and polystyrene arrays require microscopes to focus through the thickness of an amorphous bottom plate with its inherent chromatic aberrations to capture the image in the well.

INCOM can customize microwell arrays to specification.

Incom’s microarray plates for genetic sequencing have exponentially expanded the number of analytical sites in a 1″ x 3″ slide to greater than 1 million.